LAIR1 Protein (AA 22-125)
Quick Overview for LAIR1 Protein (AA 22-125) (ABIN666805)
Target
See all LAIR1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 22-125
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Sequence
- MQEEDLPRPS ISAEPGTVIP LGSHVTFVCR GPVGVQTFRL ERESRSTYND TEDVSQASPS ESEARFRIDS VSEGNAGPYR CIYYKPPKWS EQSDYLELLV KETSG
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Characteristics
- LAIR-1( Extracellular domain , 22-125aa, human), Recombinant, E.coli
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Purification
- > 95% by SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 7.5) containing 50 mM NaCl, 1 mM EDTA
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
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Alternative Name
- LAIR1
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Background
- LAIR-1 is a glycoprotein (~32 kDa) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. The extracellular domain of LAIR-1 ( 22-125aa) was overexpressed in E. coli, and purified by using conventional chromatography techniques.
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Molecular Weight
- 11.7 kDa (105aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_002278
Target
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